EVALUATION OF CEFOTAXIME USE IN BAQUBA TEACHING HOSPITAL تقييم استعمال عقار سيفوتاكسيم في مستشفى بعقوبة التعليمي

الملخص

Background:

          Antibiotics are one of the most commonly prescribed drugs today. Rational use of antibiotics is extremely important as injudicious use can adversely affect the patient, cause emergence of antibiotic resistance and increase the cost of health care; Antibiotics resistance is out of the scope of this study.

Methods:

                   This study was carried out on (686) patients with age range (39.4±20.9 years), of both sexes; to whom cefotaxime was prescribed for different medical and surgical causes in Baquba Teaching Hospital- Diyala; over the period of three months. The selected patients were allocated into 2 groups: Group A (650) patients to whom cefotaxime prescribed without considering any guidelines for antibiotic prescription, compared with group B (36) patients to whom cefotaxime prescribed depending on standard guideline. To each group the following information were collected: age, sex, diagnosis, number of days were cefotaxime used, dose given, laboratory tests done to patients during hospitalization and drug interaction if present in addition to other parameters designed according to this study.

Results:

          Results obtained in this study showed that prescription of cefotaxime depending on standard guideline of antibiotic improve the cefotaxime true    dose %, reduce occurrence of drug interaction (%), decrease significantly (P<0.05) cefotaxime misuse ratio and significantly (P<0.05) reduce amount and cost of cefotaxime prescribed per month.

Conclusion:

          Strictly following standard guidelines for antibiotic prescription; and involvement of clinical pharmacist in the team work improve therapeutic process outcome, prevent many problems like adverse effects and high cost and lead to rational use of antibiotic-the dream of many therapist-.