Synthesis of Barbiturate Derivatives from Imines توليف مشتقات الباربيتورات من Imines
محتوى المقالة الرئيسي
الملخص
Barbiturates were prepared involving the reaction of aromatic Schiff bases with benzoyl chloride to give N-[α-chloro-α-dimethylaminobezyl]-N-aryl-benzanilide. The reaction of the latter with diethylmalonate in basic media to give N-[α-diethylmalonyl-α-p-dimethylaminobenzyl]-N-aryl-benzanilide. The latter condense with urea in basic media afforded derivatives of barbiturate which known to act as hypnotics.
##plugins.themes.bootstrap3.displayStats.downloads##
##plugins.themes.bootstrap3.displayStats.noStats##
تفاصيل المقالة
القسم
بحـــــــوث العــــــدد