Synthesis of Schiff bases of 2-thio-5-aryl-1,3,4-oxadiazole derivatives of possible biological activity

Abstract

In this study, new derivatives of Schiff bases of 2-thio-5-aryl-1,3,4-oxadiazole have been synthesized. The structures of these derivatives were characterized from their melting points, infrared spectroscopy and elemental analysis.

The Schiff bases derivatives were tested for inhibition of E-coli and were all found to be active.