Prognosis of ALP, LDH, TP and Ca levels through the chemotherapy in Iraqi Patients with Multiple Myeloma

Abstract

       Twenty seven patients with multiple myeloma were included in this study and twenty seven a house hold relatives were taken as a control preferred age and sex match. Serum Alkaline phosphatase ALP, Lactate dehydrogenase LDH, total protein TP and calcium Ca levels were determined before and after the first course of chemotherapy treatment ,its about six weeks, using kits from Randox  and Biomaghreb Companeis.

  Serum ALP, LDH, TP and Ca levels before and after treatment were significantly higher than control groups, also their levels before treatment were significantly higher than after treatment. 

     There is a different change in the level of ALP, LDH, TP and Ca in serum of multiple myeloma patients before and after chemotherapy treatment as compared with control. Further investigation needed to estimate the accurate cases of these changes, assessing the disease severity, progression and to detect early relapse